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Posts by Collection
portfolio
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publications
Characterization of DNA aptamer–protein binding using fluorescence anisotropy assays in low volume, high-efficiency plates
Published in Analytical Methods, 2021
Recommended citation: Weaver, SD., Whelan, RJ. (2021). "Characterization of DNA aptamer–protein binding using fluorescence anisotropy assays in low volume, high-efficiency plates" Analytical Methods. 13, 1302-1307. DOI: 10.1039/D0AY02256J. https://pubs.rsc.org/en/content/articlehtml/2021/ay/d0ay02256j
Preparative capillary electrophoresis (CE) fractionation of protein digests improves protein and peptide identification in bottom-up proteomics
Published in Analytical Methods, 2022
Recommended citation: Weaver, SD., Schuster-Little, N. Whelan, RJ. (2022). "Preparative capillary electrophoresis (CE) fractionation of protein digests improves protein and peptide identification in bottom-up proteomics" Analytical Methods. 14, 1103-1110. DOI: 10.1039/D1AY02145A. https://pubs.rsc.org/en/content/articlelanding/2022/ay/d1ay02145a/unauth
Activity: Teaching Coding in R through Discipline-Focused Problem-Solving in an Analytical Chemistry Course
Published in Journal of Chemical Education, 2022
Recommended citation: Weaver, SD., Ambrose, GA. Whelan, RJ. (2022). "Activity: Teaching Coding in R through Discipline-Focused Problem-Solving in an Analytical Chemistry Course" Journal of Chemical Education. 99, 3068-3073. DOI:10.1021/acs.jchemed.2c00395 https://pubs.acs.org/doi/full/10.1021/acs.jchemed.2c00395
PrIntMap-R: an online application for intra-protein intensity and peptide visualization in bottom-up proteomics
Published in Journal of Proteome Research, 2023
Recommended citation: Weaver, SD., DeRosa, CM., Schultz, SR., Champion, MM. (2023). "PrIntMap-R: an online application for intra-protein intensity and peptide visualization in bottom-up proteomics" Journal of Proteome Research. 22 (2), 432–441. DOI: 10.1021/acs.jproteome.2c00606 https://pubs.acs.org/doi/10.1021/acs.jproteome.2c00606?ref=pdf
Simultaneous N-deglycosylation and digestion of complex samples on S-Traps enables efficient glycosite hypothesis generation
Published in ACS Omega, 2023
Recommended citation: DeRosa, CM., Weaver, SD., Wang, CW., Schuster-Little, N., Whelan, RJ. (2022) "Simultaneous N-deglycosylation and digestion of complex samples on S-Traps enables efficient glycosite hypothesis generation". ACS Omega. 8 (4), 4410-4418. DOI: 10.1021/acsomega.2c08071 https://pubs.acs.org/doi/10.1021/acsomega.2c08071
An N-acetyltransferase required for EsxA N-terminal protein acetylation and virulence in 2 Mycobacterium marinum
Published in mBio, 2023
Recommended citation: Collars, OA., Jones, BS., Hu, DD., Weaver, SD., Sherman, TA., Champion, MM., Champion, PA. (2023) "An N-acetyltransferase required for EsxA N-terminal protein acetylation and virulence in Mycobacterium marinum". mBio. 14(5). DOI: [https://doi.org/10.1101/2023.03.14.532585](https://doi.org/10.1128/mbio.00987-23)https://doi.org/10.1128/mbio.00987-23 https://journals.asm.org/doi/10.1128/mbio.00987-23
A Revised Molecular Model of Ovarian Cancer Biomarker CA125 (MUC16) Enabled by Long-read Sequencing
Published in Cancer Research Communications, 2024
Recommended citation: Wang, CW., Weaver, SD., Boonpattrawong, N., Schuster-Little, N., Patankar, M., Whelan, RJ. (2024) "A revised molecular model of ovarian cancer biomarker CA125 (MUC16) enabled by long-read sequencing". Cancer Res Commun. 4(1). DOI: 10.1158/2767-9764.CRC-23-0327 https://aacrjournals.org/cancerrescommun/article/4/1/253/734015/A-Revised-Molecular-Model-of-Ovarian-Cancer?sf185514906=1
talks
Low-Volume Fluorescence Anisotropy Will Allow Efficient Characterization of Aptamer Binding to Deamidation Products
Published:
Poster presentation showing efficacy of low volume FA and proposing selection of aptamers towards deamidation products of pharmaceuticals.
Introducing computational programming skills to an analytical chemistry class using discipline-focused problem solving in R
Published:
Poster presentation on the efficacy of introducing coding in analytical chemistry curriculum.
Adapting bottom-up proteomics for detection of the ovarian cancer biomarker CA125/MUC16
Published:
Invited presenter in the Goshen College Science Speaker Lecture Series.
Capillary electrophoresis (CE) fractionation of complex samples in bottom-up proteomics for cancer biomarker characterization
Published:
1st Place Poster Contest Award Winner.
Using PrIntMap-R to visualize protein glycosylation sites in enzymatically deglycosylated samples
Published:
1st Place Oral Presentation Contest Winner
teaching
Organic Chemistry Teaching Assistant
Undergraduate laboratory TA, Goshen College, Chemistry, 2016
Assisted in the laboratory sessions for Organic Chemistry I and II. Set up labs, answered quesitons during experiments, graded laboratory reports and notebooks.
Biochemistry Teaching Assistant
Undergratuate laboratory TA, Goshen College, Chemistry, 2017
Laboratory TA for undergraduate biochemistry class. Set up instruments, answered questions during lab, and graded lab reports.
Advanced Cell Biology Teaching Assistant
Undergraduate laboratory TA, Goshen College, Biology, 2018
Assisted in the laboratory sessions for Advanced Cell Biology. Set up labs, answered quesitons during cell culture, graded laboratory reports and notebooks.
Guest Lecturer - Analytical Chemistry
Guest Lecturer for undergraduates, Analytical Chemstiry, University of Notre Dame, Chemistry, 2022
Lectured on the importance of programming in analytical chemsitry. Presented an online activity I designed to engage students in discipline focussed problem solving using R.